Surgical Reference

Oral & Maxillofacial
Microvascular Reconstruction

A comprehensive surgical summary of workhorse flaps utilized in maxillofacial reconstructive surgery, detailing vascular anatomy, indications, and harvest design.

Osteocutaneous Free Flap Gold Standard Bone

Fibula Free Flap (FFF)

Vascular Anatomy

  • Artery: Peroneal Artery (Branch of tibioperoneal trunk)
  • Vein(s): Peroneal Venae Comitantes (usually 2, join to form common peroneal vein)
  • Pedicle Length: 5-8 cm (Can be extended by harvesting more proximal bone and discarding it)
  • Vessel Diameter: Artery 1.5-2.5mm, Veins 2.0-3.0mm

Indications

  • Large mandibular defects (>6 cm).
  • Maxillary reconstruction (Brown Class II-IV).
  • Requirements for osseointegrated dental implants (provides excellent cortical bone stock).
  • Composite defects requiring bone and moderate soft tissue (skin paddle).

Flap Design & Harvest

Pre-op: CTA/MRA or lower extremity angiogram to confirm 3-vessel runoff to the foot.

Bone Harvest: Lateral aspect of lower leg. Up to 25cm of bone available. Crucial rule: Must preserve 6-8 cm of distal fibula (ankle stability) and proximal fibula (knee stability/fibular nerve).

Skin Paddle: Designed over the posterolateral intermuscular septum. Relies on septocutaneous perforators (usually lower 1/3 to middle 1/3 of leg).

Included Muscle(s): A 1-2 cm cuff of the Flexor Hallucis Longus (FHL) and Tibialis Posterior is typically retained along the posterior/medial aspect of the bone to protect the peroneal vessels. A larger segment of the Soleus or FHL can be included if extra soft-tissue bulk is required.

Modification: Can be osteotomized multiple times (closing wedges) to perfectly mimic the mandibular curve.

Anatomical Landmarks & Design Diagram

Schematic
DO NOT HARVEST Proximal 6-8cm (Nerve) DO NOT HARVEST Distal 6-8cm (Ankle) Harvestable Bone Peroneal Artery Peroneal Vein(s) Skin Paddle (Septocutaneous)
Fasciocutaneous Free Flap

Radial Forearm Free Flap (RFFF)

Vascular Anatomy

  • Artery: Radial Artery
  • Vein(s): Cephalic Vein (superficial system) and Radial Venae Comitantes (deep system). Usually both are harvested.
  • Pedicle Length: Exceptionally long, up to 15-20 cm.
  • Vessel Diameter: Artery 2.0-3.0mm, Veins 2.5-4.0mm (Cephalic).

Indications

  • Intraoral soft tissue defects (tongue, floor of mouth, buccal mucosa).
  • Defects requiring thin, pliable, hairless tissue for excellent functional mobility.
  • Facial skin resurfacing.
  • Can be innervated (lateral antebrachial cutaneous nerve) for sensate reconstructions.

Flap Design & Harvest

Pre-op: Allen's test is absolutely mandatory to ensure ulnar artery collateral perfusion to the hand.

Harvest: Volar aspect of the non-dominant forearm. Designed over the course of the radial artery between the brachioradialis and flexor carpi radialis (FCR).

Dissection: Subfascial plane, ensuring paratenon over flexor tendons is preserved to allow for split-thickness skin graft (STSG) take.

Included Muscle(s): None (Strictly fasciocutaneous). The flap is elevated off the underlying Brachioradialis and Flexor Carpi Radialis muscles, which are preserved in the donor bed.

Note: Donor site morbidity includes aesthetic defect, potential decreased grip strength, and need for STSG.

Anatomical Landmarks & Design Diagram

Schematic
Radial Artery Ulnar Artery Palmar Arch (Check via Allen's Test) Fasciocutaneous Skin Paddle Volar Forearm
Osteocutaneous Free Flap

Osteocutaneous Radial Forearm

Vascular Anatomy

Identical to standard RFFF. The bone is perfused via periosteal branches from the radial artery traveling in the lateral intermuscular septum.

Indications

  • Small, non-load-bearing composite defects.
  • Mandibular defects < 3-4 cm combined with large soft tissue requirement.
  • Palate and maxillectomy defects (Class I-II).

Flap Design & Bone Harvest

Same soft tissue design as RFFF. Include a segment of the radius along the intermuscular septum.

Included Muscle(s): None (Minimal). Only a very small cuff of the Flexor Pollicis Longus (FPL) and Pronator Quadratus muscular attachments are retained specifically to preserve the periosteal blood supply to the harvested bone segment.

Critical Constraint:

Bone harvest is limited to a maximum of 10-12 cm in length and strictly no more than 40% of the cross-sectional circumference of the radius.

Post-op: Prophylactic plating of the radius (keel shape cut preferred) and prolonged immobilization are often required to prevent pathological fracture.

Anatomical Landmarks & Design Diagram

Schematic
Harvested Bone Segment (Max 40% Circumference) Remaining Radius Bone (Plated prophylactically) Radial Artery & Venae Comitantes (Feeding periosteum)
Osteocutaneous / Osteomuscular Maximum Bone Height

Iliac Crest Bone Flap (DCIA)

Vascular Anatomy

  • Artery: Deep Circumflex Iliac Artery (DCIA), branch of external iliac.
  • Vein(s): Deep Circumflex Iliac Vein (DCIV), drains into external iliac vein.
  • Pedicle Length: Short (5-7 cm). Often requires vein grafts if neck vessels are depleted.

Indications

  • Defects requiring massive vertical bone height (native crest provides 12-16mm, ideal for osseointegrated implants).
  • Mandibular angle and ascending ramus reconstruction (naturally mimics the curve).
  • Large maxillary (Brown Class III-IV) composite defects.

Flap Design & Bone Harvest

Bone Harvest: Taken from the anterior ilium starting ~2cm posterior to the Anterior Superior Iliac Spine (ASIS). Can be harvested as an inner table block or a full-thickness bicortical segment.

Included Muscle(s): The Internal Oblique muscle is frequently co-harvested (based on the ascending branch of the DCIA) to provide bulky, reliable, mucosalized soft tissue coverage for the oral cavity. A small cuff of Transversus Abdominis and External Oblique is retained over the inner crest to protect the pedicle.

Donor Site Note: High morbidity risk. Requires meticulous multilayer abdominal wall closure to prevent hernia formation. Patients may experience temporary lateral femoral cutaneous nerve neuropraxia and gait disturbances.

Anatomical Landmarks & Design Diagram

Schematic
ASIS Harvested Bone Block DCIA Pedicle (Deep to crest) Internal Oblique Muscle
Fasciocutaneous / Myocutaneous Workhorse Soft Tissue

Anterolateral Thigh (ALT)

Vascular Anatomy

  • Artery: Descending branch of the Lateral Circumflex Femoral Artery (LCFA).
  • Vein(s): Venae comitantes to LCFA.
  • Perforators: Relies on musculocutaneous perforators (80%) through vastus lateralis or septocutaneous (20%).
  • Pedicle Length: 8-16 cm.

Indications

  • Massive soft tissue defects (total glossectomy, skull base, large scalp/neck).
  • Through-and-through cheek defects (can be folded or bipaddled).
  • When primary closure of donor site is preferred (unlike RFFF).

Flap Design & Harvest

Design: Axis is a line drawn from ASIS to superolateral patella. Perforators usually found within a 3cm radius of the midpoint of this line.

Harvest: Subfascial or suprafascial dissection. Identifying and tracing perforators through the vastus lateralis muscle requires meticulous microsurgical technique.

Included Muscle(s): Variable. Can be harvested as a pure fasciocutaneous flap (no muscle) by meticulously dissecting perforators free, or as a myocutaneous/chimeric flap including a portion or the entirety of the Vastus Lateralis muscle for dead space obliteration.

Versatility: Can be thinned primarily (microdissection of subcutaneous fat) or harvested as a chimeric flap (skin paddle + separate vastus lateralis muscle block on same pedicle for dead space obliteration).

Donor site generally closed primarily if width is < 8-10 cm.

Anatomical Landmarks & Design Diagram

Schematic
ASIS (Hip Marker) Superolateral Patella Axis Midpoint 3cm Radius (Perforator Zone) Fasciocutaneous Paddle (Centered on perforators)
Fasciocutaneous Free Flap Forearm Alternative

Lateral Upper Arm Flap (LAF)

Vascular Anatomy

  • Artery: Posterior Radial Collateral Artery (PRCA), a terminal branch of the profunda brachii artery.
  • Vein(s): Venae comitantes to the PRCA.
  • Pedicle Length: Moderate (6-8 cm).

Indications

  • Small to moderate oral cavity defects (tongue, floor of mouth, buccal mucosa).
  • Excellent substitute for the RFFF when Allen's test is abnormal or to avoid cosmetically obvious forearm scarring.
  • Can provide a slightly thicker and more robust skin paddle than the distal forearm.

Flap Design & Harvest

Design: The flap is centered over the lateral intermuscular septum of the arm. The axis is a line drawn from the deltoid insertion down to the lateral epicondyle of the humerus.

Included Muscle(s): None (Strictly fasciocutaneous). The flap is elevated off the triceps posteriorly and the brachialis/brachioradialis anteriorly. A very thin rim of triceps fascia is sometimes preserved around the septum to protect the perforating vessels.

Donor Site: Widths up to 6-8 cm can usually be closed primarily. If primary closure is achieved, the resulting linear scar is easily hidden beneath short sleeves.

Anatomical Landmarks & Design Diagram

Schematic
Deltoid Insertion Lateral Epicondyle Lateral Intermuscular Septum PRCA Pedicle Skin Paddle (Fasciocutaneous)
Pedicled Myocutaneous

Pedicled Pectoralis Major (PMF)

Vascular Anatomy

  • Dominant Pedicle: Pectoral branch of the Thoracoacromial Artery and Vein.
  • Course: Exits clavipectoral fascia deep to the muscle, courses medial to the coracoid process, descending inferomedially on the undersurface of the muscle.

Indications

  • "Workhorse" for salvage reconstruction or vessel-depleted necks (post-radiation/failed free flaps).
  • Patients medically unfit for prolonged free flap surgery.
  • Carotid blowout prophylaxis (muscle coverage).
  • Oral cavity, oropharynx, and neck skin defects.

Flap Design & Harvest

Design: Skin paddle drawn inferomedially to the nipple/areola complex (to capture random musculocutaneous perforators). Muscle is released from humeral, clavicular, and sternal attachments.

Included Muscle(s): Pectoralis Major. The muscle itself acts as the vascular carrier for the overlying skin paddle and provides significant bulk to cover neurovascular structures in the neck.

Arc of Rotation: Rotated up to 180 degrees into the neck/face over the clavicle. Clavicle can act as a fulcrum and compress the pedicle; occasionally a portion of clavicle is removed or the flap is tunneled beneath it.

Drawbacks: Bulky (especially in women with breast tissue), creates neck tethering, significant chest wall deformity, gravity pulls flap down over time.

Anatomical Landmarks & Design Diagram

Schematic
Clavicle Sternum Pectoralis Major Muscle Nipple/Areola Skin Paddle (Inferomedial) Rotate 180° Over clavicle into neck
Pedicled / Free Myocutaneous

Latissimus Dorsi (LD)

Vascular Anatomy

  • Dominant Pedicle: Thoracodorsal Artery & Vein (continuation of subscapular system).
  • Pedicle Length: Up to 10-12 cm.
  • Vessel Diameter: Large caliber (2.5 - 3.5mm), very reliable.

Indications

  • Massive soft tissue defects requiring tremendous surface area (e.g., near-total scalp defects).
  • Can be utilized as a Free Flap (microsurgical) or Pedicled Flap.
  • Pedicled used for lower neck or posterior scalp reconstruction.

Flap Design & Harvest

Design: Extremely large skin paddles (e.g., 10x20 cm) can be harvested safely. Can also harvest muscle alone and cover with STSG.

Harvest (Pedicled): Muscle detached from spine/iliac crest. Pedicle isolated in the axilla. Flap is tunneled through the axilla to the neck.

Included Muscle(s): Latissimus Dorsi. Often harvested as a large myocutaneous flap or a muscle-only flap. (The Serratus Anterior muscle can occasionally be co-harvested based on the subscapular system for chimeric needs).

Logistical Note: Requires patient to be placed in lateral decubitus position during surgery, which can complicate simultaneous two-team approaches (ablative + reconstructive) compared to ALT or forearm.

Anatomical Landmarks & Design Diagram

Schematic
Spine (Midline) Thoracodorsal Pedicle (Axilla) Latissimus Dorsi Muscle Skin Paddle (Designed obliquely over muscle)
Axial & Random Pattern Intraoral Workhorses

Local & Regional Flaps

When microvascular free tissue transfer is contraindicated, or for smaller defects (< 4-5 cm) where free flaps would provide excessive bulk, local and regional flaps offer highly reliable, tissue-matched reconstructive solutions with minimal donor site morbidity.

Buccal Fat Pad (BFP)

Buccal / Deep Temporal Art.

Easily harvested via a small mucosal incision superior to the maxillary molars. Excellent for closing moderate Oroantral Communications (OAC) or posterior palatal defects.

Clinical Pearl: Naturally epithelializes in the oral cavity over 3-4 weeks. Do not over-stretch to avoid ischemic necrosis.

FAMM Flap

Facial Artery/Vein

Facial Artery Musculomucosal flap. Can be pedicled superiorly (retrograde flow) or inferiorly (anterograde flow). Ideal for floor of mouth, alveolar ridge, and soft palate.

Caution: If an inferiorly pedicled FAMM is planned, the facial artery MUST be preserved during concurrent neck dissection.

Nasolabial Flap

Facial Art. Perforators

Harvested from the nasolabial fold and tunneled through the cheek (transbuccal) for anterior intraoral defects. Scar is easily hidden in the natural facial crease.

Use Case: Anterior floor of mouth, ventral tongue, and lip reconstructions.

Palatal Island Flap

Greater Palatine Art.

A robust mucoperiosteal flap based on the descending palatine vessels exiting the greater palatine foramen. Rotated to reconstruct soft palate or maxillary defects.

Donor Site: Left to heal by secondary intention; heals rapidly with excellent tissue match.

Submental Flap

Submental Art. (Facial Br.)

Tissue from the submental space tunneled to the face or oral cavity. Excellent color match for facial skin defects.

Oncologic Risk: High risk of transferring occult Level Ia/Ib cervical lymph node metastases into the reconstructive site in SCC patients.

TPFF

Superficial Temporal Art.

Temporoparietal Fascia Flap. An ultra-thin, highly vascularized regional flap. Used for orbital floor, skull base, or as coverage over auricular frameworks.

Caution: Meticulous dissection required to avoid injury to the frontal branch of the facial nerve.

Rhomboid (Limberg)

Transposition Flap

A classic transposition flap designed around a rhombic defect with 60° and 120° angles. Uses adjacent tissue laxity to close defects with minimal tension.

Use Case: Ideal for cheek, temple, and neck defects where skin mobility is predictable.

Bilobed Flap

Double Transposition

Utilizes two adjacent lobes. The primary lobe reconstructs the main defect, while the smaller secondary lobe reconstructs the primary donor site.

Use Case: The gold standard for reconstructing circular defects of the distal third of the nose.

Cervicofacial Flap

Rotation-Advancement

A massive skin flap mobilizing tissue from the preauricular, cheek, and cervical regions. Provides excellent color and texture match for large facial defects.

Caution: Risk of distal necrosis in smokers or previously irradiated skin.

Local Skin Flap Design Principles

Geometric Schematic
Rhomboid (Limberg) Flap Single Transposition Defect 60° 120° Flap L = D Bilobed Flap Double Transposition Defect Pivot Point Lobe 1 45° Lobe 2 45°
Oncology Reference AJCC 8th Edition

Oral Cavity SCC Staging

Critical Updates in 8th Edition

The AJCC 8th Edition introduced two major paradigm shifts for oral cavity cancer: Depth of Invasion (DOI) replaced tumor thickness as a primary T-stage modifier, and Extranodal Extension (ENE) was incorporated as a primary N-stage modifier, profoundly impacting prognosis and staging.

Primary Tumor (T) Staging

  • T1
    Tumor ≤ 2 cm AND DOI ≤ 5 mm
  • T2
    Tumor ≤ 2 cm AND DOI > 5 mm to ≤ 10 mm
    OR
    Tumor > 2 cm to ≤ 4 cm AND DOI ≤ 10 mm
  • T3
    Tumor > 4 cm
    OR
    Any size tumor with DOI > 10 mm
  • T4a
    Moderately Advanced: Invades cortical bone, deep/extrinsic muscle of tongue, maxillary sinus, or skin of face.
  • T4b
    Very Advanced: Invades masticator space, pterygoid plates, skull base, or encases internal carotid artery.

Clinical Nodal (cN) Staging

  • N1
    Single ipsilateral node ≤ 3 cm, ENE(-)
  • N2a
    Single ipsilateral node > 3 cm but ≤ 6 cm, ENE(-)
  • N2b
    Multiple ipsilateral nodes, none > 6 cm, ENE(-)
  • N2c
    Bilateral or contralateral nodes, none > 6 cm, ENE(-)
  • N3a
    Any node > 6 cm, ENE(-)
  • N3b
    Any node with clinical ENE(+)
    (invasion of skin, muscle, nerve, or tethering)

Depth of Invasion (DOI) vs. Thickness

Histological Concept
Normal Mucosal Surface SCC Tumor Thickness (Top to bottom) D.O.I. (From normal line)
Ablative Oncology Concurrent Procedure

Neck Dissection (ND)

Classification Types

  • Radical Neck Dissection (RND): Removal of all ipsilateral lymph node groups (Levels I-V) along with the Spinal Accessory Nerve (SAN), Internal Jugular Vein (IJV), and Sternocleidomastoid muscle (SCM).
  • Modified Radical (MRND): Removal of Levels I-V with preservation of one or more non-lymphatic structures.
    • Type I: Preserves SAN.
    • Type II: Preserves SAN & IJV.
    • Type III: Preserves SAN, IJV & SCM (Functional).
  • Selective (SND): Preservation of one or more lymphatic groups that are routinely removed in RND (e.g., Supraomohyoid SND commonly removes I-III for oral cavity cancers).
  • Extended: RND plus additional lymph nodes (e.g., Level VI) or non-lymphatic structures (e.g., Carotid, Vagus).

Cervical Lymph Node Levels

Level I: Submental (Ia) and Submandibular (Ib). Bounded by the anterior/posterior bellies of the digastric muscle and the mandible.

Level II: Upper Jugular. Skull base down to the carotid bifurcation (clinical landmark: hyoid bone). Anterior to posterior border of SCM.

Level III: Middle Jugular. Carotid bifurcation down to the omohyoid muscle (clinical landmark: cricoid cartilage).

Level IV: Lower Jugular. Omohyoid muscle down to the clavicle.

Level V: Posterior Triangle. Posterior boundary of SCM to anterior boundary of trapezius.

Level VI: Anterior Compartment. Hyoid bone to suprasternal notch, bounded laterally by medial borders of carotid sheaths.

Sentinel Lymph Node Biopsy (SLNB)

Concept: The identification and excision of the first lymph node(s) in the lymphatic basin that drains a primary tumor. If the sentinel node is negative for metastasis, the rest of the nodal basin is presumed disease-free.

Primary Indication: Early-stage (T1-T2) Oral Cavity Squamous Cell Carcinoma (OCSCC) with a clinically and radiologically negative neck (cN0).

Technique: Involves preoperative peritumoral injection of a radiotracer (e.g., Technetium-99m) and/or intraoperative blue dye. The sentinel node is localized during surgery using a handheld gamma probe.

Clinical Benefit

Significantly reduces morbidity associated with an elective neck dissection (e.g., shoulder dysfunction, contour defects, prolonged drainage) in patients who do not actually harbor occult metastases.

Anatomical Neck Levels Diagram

Lateral View
I II III IV V VI Anatomical Landmarks Sternocleidomastoid (SCM) Digastric / Omohyoid Boundaries • I/II split: Hyoid Bone • II/III split: Carotid Bifurcation • III/IV split: Omohyoid Muscle

Supplemental Flaps

Gracilis Flap

Medial Circumflex Femoral

Muscle-only free flap heavily utilized for dynamic facial reanimation (treating facial paralysis). A small, consistent muscle belly that can be innervated by the masseteric or cross-facial nerve graft.

Scapular System

Circumflex Scapular / Thoracodorsal

Osteocutaneous or chimeric free flap. Excellent for complex 3D defects with independent skin and bone paddles (parascapular/scapular skin + lateral border scapula bone). Drawback: Requires repositioning (lateral/prone).

Supraclavicular (SCAIF)

Transverse Cervical Art.

Thin, pliable regional fasciocutaneous flap harvested from the shoulder/supraclavicular region. An excellent alternative to free tissue transfer for vessel-depleted necks, tracheostoma defects, or patients with severe medical comorbidities.

Knowledge Check

Test your retention of the vascular anatomy, landmarks, and surgical principles of OMFS reconstructive flaps with this comprehensive bank.

Total Questions 66
Format Multiple Choice
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